Main Psyconeurological Disorders Affecting Gastrointestinal Functions

 PSYCHIC

• Psychiatric disorders
• Somatization*
• Health anxiety*
• Conversion syndrome*

BRAIN

• Cerebrovascular accidents (USA: 400,000; GI Dysfunctions > 40%)
• Head injury
• Movement disorders (Parkinsonism) (70-180/100,000; GI Dysfunctions > 55%)
• Multiple sclerosis (USA: 250,000; GI Dysfunctions 68%)
• Cerebral Palsy -Alzheimer's d (4% population > 65 yrs)

SPINAL CORD

• Traumatic lesions
• Spina bifida (1-4/1,000 live births; GI Dysfunctions > 75%)
• Multiple sclerosis (USA: 250,000; GI Dysfunctions 68%)

AUTONOMIC NERVOUS SYSTEM

• Sympathetic dysfunction *
• Parasympathetic dysfunction *
• Dorsal horn neurons sensitization *
• Autonomic (diabetic) neuropathy

 See also ANS

ENTERIC NERVOUS SYSTEM

• Achalasia (1:100,000)
• Hirschsprung's d (1:6,000 live births)
• Visceral neuropathy (neuronal intestinal dysplasia, hyperganglionosis, paraneoplastic; Infectious; myopathies)
• Sensory neurons sensitization * *

See also ENS

The sum of these conditions about 40% of the GI patient population